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Faculty of Mathematics and Natural SciencesCologne Crystallisation Facility

Since Beginning of 2018 the following papers were generated with the help of C2f.

Congratulations to all the authors!

 If you plan to publish a paper, it would be very helpful if you mention us in the acknowledgments.

2025

  • Hermanns, T., Kolek, S., Uthoff, M., de Heiden, R. A., Mulder, M. P. C., Baumann, U., and Hofmann, K. (2025) A family of bacterial Josephin-like deubiquitinases with an irreversible cleavage mode. Mol Cell. 10.1016/j.molcel.2025.02.002

2024

  • Atomwise AIMS Program (2024) AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep. 14, 7526
  • Kremer, M., Schulze, S., Eisenbruch, N., Nagel, F., Vogt, R., Berndt, L., Dörre, B., Palm, G. J., Hoppen, J., Girbardt, B., Albrecht, D., Sievers, S., Delcea, M., Baumann, U., Schnetz, K., and Lammers, M. (2024) Bacteria employ lysine acetylation of transcriptional regulators to adapt gene expression to cellular metabolism. Nat Commun. 15, 1674
  • Hermanns, T., Uthoff, M., Baumann, U., and Hofmann, K. (2024) The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance. 7, e202302422

2023

  • Hermanns, T., Uthoff, M., Baumann, U., and Hofmann, K. (2024) The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Science Alliance. 10.26508/lsa.202302422

  • Boll, V., Hermanns, T., Uthoff, M., Erven, I., Hörner, E.-M., Kozjak-Pavlovic, V., Baumann, U., & Hofmann, K. (2023). Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis. Nature Communications, 14(1), 7335. https://doi.org/10.1038/s41467-023-43144-y

  • Cao, Y., Kümmel, F., Logemann, E., Gebauer, J. M., Lawson, A. W., Yu, D., Uthoff, M., Keller, B., Jirschitzka, J., Baumann, U., Tsuda, K., Chai, J., and Schulze-Lefert, P. (2023) Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors. Proceedings of the National Academy of Sciences. 120, e2307604120

2022

  • Jia, A., Huang, S., Song, W., Wang, J., Meng, Y., Sun, Y., Xu, L., Laessle, H., Jirschitzka, J., Hou, J., Zhang, T., Yu, W., Hessler, G., Li, E., Ma, S., Yu, D., Gebauer, J., Baumann, U., Liu, X., Han, Z., Chang, J., Parker, J. E., and Chai, J. (2022) TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity. Science. 377, eabq8180

  • Erven, I., Abraham, E., Hermanns, T., Baumann, U., & Hofmann, K. (2022). A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nature Communications, 13(1), 7643. https://doi.org/10.1038/s41467-022-35244-y

2021

  • Abraham, E. T., Oecal, S., Mörgelin, M., Schmid, P. W. N., Buchner, J., Baumann, U., and Gebauer, J. M. (2021) Collagen’s primary structure determines collagen:HSP47 complex stoichiometry. Journal of Biological Chemistry. 10.1016/j.jbc.2021.101169

2020

  • Maaßen, A., Gebauer, J. M., Theres Abraham, E., Grimm, I., Neudörfl, J.-M., Kühne, R., Neundorf, I., Baumann, U., and Schmalz, H.-G. (2020) Triple-Helix-Stabilizing Effects in Collagen Model Peptides Containing PPII-Helix-Preorganized Diproline Modules. Angew. Chem. Int. Ed. Engl. 10.1002/anie.201914101

  • Solomon-Degefa, H., Gebauer, J. M., Jeffries, C. M., Freiburg, C. D., Meckelburg, P., Bird, L. E., Baumann, U., Svergun, D. I., Owens, R. J., Werner, J. M., Behrmann, E., Paulsson, M., and Wagener, R. (2020) Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. Journal of Biological Chemistry. 295, 12755–12771

2019

  • Pichlo, C., Juetten, L., Wojtalla, F., Schacherl, M., Diaz, D., and Baumann, U. (2019) Molecular determinants of the mechanism and substrate specificity of Clostridium difficile proline-proline endopeptidase-1. J. Biol. Chem. 10.1074/jbc.RA119.009029

2018

  • Gebauer, J. M., Köhler, A., Dietmar, H., Gompert, M., Neundorf, I., Zaucke, F., Koch, M., and Baumann, U. (2018) COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens. Sci Rep. 8, 17187
  • Pichlo, C., Toelzer, C., Chojnacki, K., Öcal, S., Uthoff, M., Ruegenberg, S., Hermanns, T., Schacherl, M., Denzel, M. S., Hofmann, K., Niefind, K., and Baumann, U. (2018) Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Cryst F (2018) in press
  • Uthoff, M., and Baumann, U. (2018) Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA+ protease FtsH. Journal of Structural Biology. 10.1016/j.jsb.2018.08.009